We’ve seen plenty of examples of a tiny drop of isopropyl alcohol and a bit of light agitation with a cotton swab being more than enough to loosen up even the nastiest baked-on flux. If we do ...

While the static structure of the nuclear pore complex (NPC) continues to be refined with cryo-EM and x-ray crystallography, in vivo conformational changes of the NPC remain under-explored. We ...

Assembly of bacterial ring-shaped hexameric replicative helicases on single-stranded (ss) DNA requires specialized loading factors. However, mechanisms implemented by ...