Although gut microbiota and lipid metabolites have been suggested to be closely associated with type 2 diabetes mellitus (T2DM), the interactions between gut microbiota, ...

Lung cancer is a particularly challenging form of cancer. It often strikes unexpectedly and aggressively with little warning, and it can shapeshift in unpredictable ways to evade treatment.

Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs). Here, using a ...

Cell cycle re-entry of senescent breast cancer cells after CDK4/6 inhibition (CDK4/6i) constitutes a major source of disease ...

Alcohol use disorder, which affects over 10% of Americans, can lead to persistent and serious insomnia. Difficulties falling ...

Research in fruit flies has identified specific groups of cholinergic brain cells that are involved in alcohol-induced insomnia. This work could ultimately lead to targeted treatments for ...

Diabetes, as defined by the World Health Organization, represents a collection of metabolic diseases characterized primarily by hyperglycemia, which can ...

Single-nuclei multiomics analyses of ovarian tissue from young and reproductively aged individuals reveal mTOR signaling as an ovary-specific aging pathway ... A Nature Metabolism study identifies ...

Metabolic engineering is the use of genetic engineering to modify the metabolism of an organism. It can involve the optimization of existing biochemical pathways or the introduction of pathway ...

KUCHING: After successfully producing and exporting methanol, Sarawak Petchem Sdn Bhd is now setting sights on another new product – green methanol. Sarawak Premier Tan Sri Abang Johari Tun ...

Furthermore, impaired muscle integrity, defined as persistent muscle loss, intramuscular lipid accumulation, or connective tissue deposition, is a hallmark of metabolic dysfunction. In fact, many ...

Metabolic pathway enrichment was accomplished via MetaboAnalyst V.5.0.28 GraphPad Prism V.9.0 (GraphPad Software) was used for statistical treatment. Experimental data was shown as mean±SEM.