JAK-STAT signaling pathway - Wikipedia
The JAK-STAT signaling pathway is a chain of interactions between proteins in a cell, and is involved in processes such as immunity, cell division, cell death, and tumor formation.
The JAK/STAT signaling pathway: from bench to clinic - PMC
In addition to the main components of the JAK/STAT signaling pathway, many related proteins play indispensable roles in STAT-dependent transcription and JAK–STAT interactions with …
Pharmacological targeting of the JAK–STAT pathway: new
Jan 5, 2026 · The Janus kinase (JAK)–signal transducer and activator of transcription (STAT) pathway mediates cellular responses to cytokines and growth factors, and its dysregulation …
JAK/STAT pathway: Extracellular signals, diseases, immunity, and ...
Feb 23, 2023 · In this review, we discuss the role of the JAK/STAT pathway in mechanistic signaling, disease progression, immune environment, and therapeutic targets.
JAK-STAT Signaling Pathway - an overview - ScienceDirect
The JAK-STAT signaling pathway is defined as a cytokine-stimulated signaling pathway involved in various biological processes, including cell proliferation, differentiation, apoptosis, and …
What Is JAK-STAT Signaling and How Does It Work?
Aug 1, 2025 · The JAK-STAT pathway is involved in numerous physiological processes, demonstrating its importance for maintaining health. It plays a significant role in immune …
JAK-STAT signaling pathway - Cusabio
In mammals, the JAK/STAT pathway is the principal signaling mechanism for a wide array of cytokines and growth factors. Following the binding of cytokines to their cognate receptor, …
KEGG PATHWAY: JAK-STAT signaling pathway - Homo sapiens …
In mammals, the JAK/STAT pathway is the principal signaling mechanism for a wide array of cytokines and growth factors. Following the binding of cytokines to their cognate receptor, …
The JAK-STAT pathway: from structural biology to cytokine
Aug 21, 2024 · In this review, we outline the structural basis that governs key nodes in this pathway, offering a comprehensive overview of the signal transduction process. Furthermore, …
The JAK-STAT pathway at 30: Much learned, much more to do
Oct 13, 2022 · In recognition of the many publications and reviews published since the birth of the JAK-STAT pathway, we now strive to synthesize the salient findings and concepts, hoping to …