Dire Wolf Puppy Cries Heard for the First Time in 10,000 Years In a groundbreaking achievement, scientists at Colossal Biosciences have successfully brought dire wolves back to life after their extinction approximately 12,500 years ago. By extracting DNA from ancient fossils—a 13,000-year-old tooth and a 72,000-year-old skull—the team reconstructed the dire wolf genome. They then used CRISPR gene-editing technology to modify gray wolf DNA, introducing 20 specific edits across 14 genes to replica
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