Loop Diuretics (furosemide) Mechanism of Action and Pharmacology
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YouTubePharmacology Notes
Loop Diuretics (furosemide) Mechanism of Action and Pharmacology
Loop Diuretics (Furesemide, torsemide, bumetanide and Ethacrynic Acid) are the inhibitors of Na/K/2Cl cotransport system in thick ascending limb of loop of Henle. Drugs in this category are: furosemide bumetanide torsemide ethacrynic acid Loop diuretics inhibit the Na+/K+/2Cl− co-transporter channel in the ascending limb of the lop of henle ...
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Remember the “D’s of Diuretics” & the 3 different types! → 💧Loop diuretics Examples: Furosemide (Lasix), Bumetanide (Bumex) ⭐Potassium (K ) wasting = Risk for hypokalemia (low potassium levels) 💧Thiazide diuretics Examples: Hydrochlorothiazide, Chlorothiazide Potassium (K ) wasting = Risk for hypokalemia (low potassium levels) 💡 “THiazide = THere goes the potassium!” 💧Potassium sparing diuretics Example: Spironolactone (Aldactone) ⭐Potassium SPARING diuretic= Risk for hyperkalemia (elevated
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The exam says acute pulmonary edema and expects you to know the drug 👀💧 Furosemide = Loop diuretic Blocks Na⁺/K⁺/2Cl⁻ in the Loop of Henle → strong diuresis. High-yield trick: Loops lose Ca²⁺ Thiazides keep Ca²⁺ Side effects? Remember OHH DAANG 😎 👂 Ototoxicity ⬇️ Hypokalemia ⬇️ Hypomagnesemia 💧 Dehydration ⚠️ Sulfa allergy Follow for daily USMLE pharmacology in Arabic English 🚀 DM “USMLE” if you want a structured Step 1 plan. #USMLE #USMLEStep1 #MedTok #Pharmacology #Furosemide
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The exam says acute pulmonary edema and expects you to know the drug 👀💧 Furosemide = Loop diuretic Blocks Na⁺/K⁺/2Cl⁻ in the Loop of Henle → strong diuresis. High-yield trick: Loops lose Ca²⁺ Thiazides keep Ca²⁺ Side effects? Remember OHH DAANG 😎 👂 Ototoxicity ⬇️ Hypokalemia ⬇️ Hypomagnesemia 💧 Dehydration ⚠️ Sulfa allergy Follow for daily USMLE pharmacology in Arabic English 🚀 DM “USMLE” if you want a structured Step 1 plan. #USMLE #USMLEStep1 #MedTok #Pharmacology #Furosemide
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Remember the “D’s of Diuretics” & the 3 different types! → 💧Loop diuretics Examples: Furosemide (Lasix), Bumetanide (Bumex) ⭐Potassium (K ) wasting = Risk for hypokalemia (low potassium levels) 💧Thiazide diuretics Examples: Hydrochlorothiazide, Chlorothiazide Potassium (K ) wasting = Risk for hypokalemia (low potassium levels) 💡 “THiazide = THere goes the potassium!” 💧Potassium sparing diuretics Example: Spironolactone (Aldactone) ⭐Potassium SPARING diuretic= Risk for hyperkalemia (elevated
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