Most people have never heard of Low-Dose Naltrexone (LDN), but it is one of the most promising tools in modern pain care. At high doses, naltrexone is used in emergency medicine to reverse opioid overdoses. At very low doses, taken orally, it works completely differently. LDN appears to calm the overactive glial cells that surround your nerves. When these cells become overstimulated, they release inflammatory chemicals that turn up the volume on pain. By temporarily blocking certain receptors, L
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